- A Case of Hepatocellular Carcinoma with Early Multiple Recurrences after Liver Resection
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Jae Hong Ahn, Hyung Joon Yim, Seung Young Kim, Jeong Han Kim, Yeon Seok Seo, Seung Hwa Lee, Hwan Hoon Chung, Tae Jin Song, Hong Sik Lee, Sang Woo Lee, Soon Ho Um, Jai Hyun Choi, Ho Sang Ryu
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Journal of the Korean Liver Cancer Study Group. 2009;9(1):29-32. Published online June 30, 2009
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Abstract
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- Hepatic resection is a standard curative therapy for hepatocellular carcinoma (HCC) although only 10~30% of patients are
indicated due to advanced stage or poor hepatic reserve. Five year survival rate after resection was reported as a mean of
55% (25~93%), but cases of early recurrence after hepatic resection had poor prognosis. As early recurrence after hepatic
resection is the one of the most important factors that determines the prognosis, many investigators have been trying to
determine the factors associated with early recurrence. We report a case of early multiple recurrence of HCC after curative
hepatic resection probably due to microvascular invasion of tumor and too close resection margin. We would like to suggest
that additional prophylactic measures need to be sought in this group of patients because these factors may influence on early
recurrence.
- A Case of Massive Hepatocellular Carcinoma Treated by Hepatic Resection, which did not Respond to Transarterial Chemoembolization
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Jeong Han Kim, Hyung Joon Yim, Seung Young Kim, Jae Hong Ahn, Ji Hoon Kim, Yeon Seok Seo, Seung Hwa Lee, Hwan Hoon Chung, Tae Jin Song, Hong Sik Lee, Sang Woo Lee, Jai Hyun Choi
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Journal of the Korean Liver Cancer Study Group. 2009;9(1):63-66. Published online June 30, 2009
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Abstract
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- Surgical resection is the treatment of choice for hepatocellular carcinoma (HCC) in non-cirrhotic patients. The optimal
indication for resection is a single tumor in a suitable location for resection. However, limit of the tumor size is not clear.
We report a case of successful hepatic resection in patients with massive HCC sized more than 15 cm that did not respond
to transarterial chemoembolization (TACE). A 49-year-old male patient had received TACE two times for massive HCC.
However, the tumor size increased. Right hemihepatectomy was performed despite the extensive tumor size and underlying
liver cirrhosis. Ascites and wound infection were developed after resection, but the patient’s general condition got recovered
soon. Until 6 months after surgery, recurrence has not been detected. However, distant metastasis was noted at 7th month.
Although recurrence with distant metastasis was noted, we think aggressive surgical approach prolonged this patient’s
survival.
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